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Daam1 (基因名), Disheveled-associated activator of morphogenesis 1 (蛋白名), daam1_mouse.

产品名称:

Mouse Daam1/ Disheveled-associated activator of morphogenesis 1 CLIA Kit
畸形发生的相关激活剂1

货号:

U15379m

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant mouse Disheveled-associated activator of morphogenesis 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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通用注释

亚单元:

Interacts with CIP4, FNBP1 and FNBP1L. Interacts with the SH3 domains of Abl, BTK, endophilin, spectrin and SRC. Binds specifically to GTP-bound CDC42 and RHOA. Interacts with INTU; INTU mediates the indirect interaction between DAAM1 and NPHP4.

功能:

Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments (By similarity). Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells.

亚细胞位置:

Cytoplasm Cytoplasm Cytoskeleton Cilium basal body Perinuclear.

数据库链接

UniGene:

Mm.474935

SMR:

Q8BPM0

STRING:

10090.ENSMUSP00000082406

KEGG:

mmu:208846

Pfam: