CRX (基因名), Cone-rod homeobox protein (蛋白名), crx_canlf.
通用注释
亚单元:
Interacts (via the homeobox) with NRL (via the leucine-zipper domain). Interacts with PDC, RAX2, RORB and SCA7.
功能:
Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
亚细胞位置:
Nucleus
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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