CRX (基因名), Cone-rod homeobox protein (蛋白名), crx_canfa.
通用注释
亚单元:
Interacts with SCA7 (By similarity). Interacts with RAX2. Interacts (via the homeobox) with NRL (via the leucine-zipper domain).
功能:
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
亚细胞位置:
Nucleus
验证序列:
该产品尚未在任何出版物中被引用。
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