Human CRHR2/ Corticotropin-releasing factor receptor 2 CLIA Kit
促肾上腺皮质激素释放因子受体2

货号:

U0241h

商标:

EIAab^®

监管等级:

RUO

别名:

Corticotropin-releasing hormone receptor 2, CRH-R-2, CRF-R-2, CRF2R, CRH2R

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant human Corticotropin-releasing factor receptor 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

关注

Human CRHR2 CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Monomer. Interacts (via N-terminal extracellular domain) with CRF, UCN, UCN2 and UCN3. Has highest affinity for UCN, and considerably lower affinity for CRF, UNC2 and UCN3.

功能:

G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

亚细胞位置:

Cell membrane Multi-pass membrane protein

数据库链接

UniGene:

Hs.546246

SMR:

Q13324

STRING:

9606.ENSP00000340943

KEGG:

hsa:1395

MIM: