Rat Cyp2e1/ Cytochrome P450 2E1 CLIA Kit
细胞色素P4502E1

货号:

U0988r

商标:

EIAab^®

监管等级:

RUO

别名:

1.14.13.n7, 4-nitrophenol 2-hydroxylase, CYPIIE1, Cytochrome P450-J, Cytochrome P450RLM6, Cyp2e, Cyp2e-1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant rat Cytochrome P450 2E1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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Rat Cyp2e1 CLIA Kit

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通用注释

亚单元:

Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.

功能:

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.

亚细胞位置:

Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein Mitochondrion inner membrane Peripheral membrane protein Post-translationally targeted to mitochondria. TOMM70 is required for the translocation across the mitochondrial outer membrane. After translocation into the matrix, associates with the inner membrane as a membrane extrinsic protein.

数据库链接

UniGene:

Rn.1372

SMR:

P05182

STRING:

10116.ENSRNOP00000016883

KEGG:

rno:25086

Pfam:

PF00067

Uniprot: