Cntnap1 (基因名), Contactin-associated protein 1 (蛋白名), cntp1_mouse.
产品名称:
Mouse Cntnap1/ Contactin-associated protein 1 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
MHDNIV, NCP1, Neurexin IV, Neurexin-4, Paranodin, Caspr, Nrxn4
检测方法:
CLIA
特异性:
Natural and recombinant mouse Contactin-associated protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts with contactin in cis form.
功能:
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells. Mice that lack CNTAP1 exhibit tremor, ataxia, and significant motor paresis. Normal paranodal junctions fail to form, and the organization of the paranodal loops is disrupted. Contactin is undetectable in the paranodes, and potassium channels are displaced from the juxtaparanodal into the paranodal domains. Also results in a severe decrease in peripheral nerve conduction velocity.
亚细胞位置:
Membrane
Single-pass type I membrane protein
数据库链接
您可能感兴趣
该产品尚未在任何出版物中被引用。
反馈墙
评论数 : 0
所有用户
所有用户
默认排序
默认排序
最近
早期
目前还没有评论。
通知
规格
数量
单价 (¥)
小计 1 (¥)
小计 2:
¥
规格
数量
单价 (¥)