CNTN1 (基因名), Contactin-1 (蛋白名), cntn1_bovin.
产品名称:
Bovine CNTN1/ Contactin-1 CLIA Kit
接触蛋白1
货号:
U15020b
商标:
EIAab®
监管等级:
别名:
Neural cell surface protein F3
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant bovine Contactin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Monomer. Interacts with CNTNAP1 in cis form (By similarity). Binds to the carbonic-anhydrase like domain of PTPRZ1. Interacts with NOTCH1 and TNR. Detected in a complex with NRCAM and PTPRB.
功能:
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.
亚细胞位置:
Cell membrane
Lipid-anchor
GPI-anchor
数据库链接
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