CNTLN (基因名), Centlein (蛋白名), cntln_human.
通用注释
亚单元:
Interacts with CEP250 and CEP68. Interacts with NEK2; the interaction leads to phosphorylation of CNTLN.
功能:
Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
亚细胞位置:
Cytoplasm
Cytoskeleton
Microtubule organizing center
Centrosome
Centriole
Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434).
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