CLN5 (基因名), Ceroid-lipofuscinosis neuronal protein 5 (蛋白名), cln5_canlf.
产品名称:
Dog CLN5/ Ceroid-lipofuscinosis neuronal protein 5 CLIA Kit
货号:
U2585d
商标:
EIAab®
监管等级:
别名:
Protein CLN5
检测方法:
CLIA
特异性:
Natural and recombinant dog Ceroid-lipofuscinosis neuronal protein 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with SORT1, RAB5A and RAB7A. Interacts with PPT1, TPP1, CLN3, CLN6, CLN8, ATP5A1 and ATP5B.
功能:
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane.
亚细胞位置:
Ceroid-lipofuscinosis neuronal protein 5
Membrane
Single-pass type II membrane protein
An amphipathic anchor region facilitates its association with the membrane.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
验证序列:
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