Dog CDC42/ Cell division control protein 42 homolog CLIA Kit
细胞分裂调控蛋白42同源物

货号:

U0321d

商标:

EIAab^®

监管等级:

RUO

别名:

G25K GTP-binding protein

检测方法:

CLIA

特异性:

Natural and recombinant dog Cell division control protein 42 homolog

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Dog CDC42 CLIA Kit

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产品说明书

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通用注释

亚单元:

Interacts with CDC42EP1, CDC42EP2, CDC42EP3, CDC42EP4, CDC42EP5, CDC42SE1, CDC42SE2, PARD6A, PARD6B and PARD6G (in a GTP-dependent manner). Interacts with activated CSPG4 and with BAIAP2. Interacts with Zizimin1/DOCK9 and Zizimin2/DOCK11, which activate it by exchanging GDP for GTP. Interacts with NET1 and ARHGAP33/TCGAP. Part of a complex with PARD3, PARD6A or PARD6B and PRKCI or PRKCZ. The GTP-bound form interacts with CCPG1 (By similarity). Interacts with USP6 (By similarity). Interacts with NEK6.

功能:

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia.

亚细胞位置:

Cell membrane Lipid-anchor Cytoplasmic side Cytoplasm cytoskeleton centrosome Co-localizes with NEK6 in the centrosome.

数据库链接

Uniprot:

P60952

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