Human CDK11A/ Cyclin-dependent kinase 11A CLIA Kit
细胞周期蛋白依赖性激酶11

货号:

U11150h

商标:

EIAab^®

监管等级:

RUO

别名:

Cell division cycle 2-like protein kinase 2, Cell division protein kinase 11A, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-protein kinase CDC2L2, CDC2L2, CDC2L3, PITSLREB

检测方法:

CLIA

特异性:

Natural and recombinant human Cyclin-dependent kinase 11A

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human CDK11A CLIA Kit

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通用注释

亚单元:

The cleaved p110 isoform, p110C, binds to the serine/threonine kinase PAK1. The p58 isoform but not the p110 isoform or p110C interacts with CCND3. The p110 isoforms are found in large molecular weight complexes containing CCNL1 and SFRS7.

功能:

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

亚细胞位置:

Cytoplasm Nucleus

数据库链接

UniGene:

Hs.651228

SMR:

Q9UQ88

STRING:

9606.ENSP00000384442

KEGG:

hsa:728642

MIM: