CCR5 (基因名), C-C chemokine receptor type 5 (蛋白名), ccr5_canfa.
产品名称:
Dog CCR5/ C-C chemokine receptor type 5 CLIA Kit
趋化因子受体5型
货号:
U2055d
商标:
EIAab®
监管等级:
别名:
CD195, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CMKBR5
检测方法:
CLIA
特异性:
Natural and recombinant dog C-C chemokine receptor type 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with PRAF2. Efficient ligand binding to CCL3/MIP-1alpha and CCL4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on Ser-6 is required for efficient binding of CCL4. Interacts with ADRBK1. Interacts with ARRB1 and ARRB2.
功能:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
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