Dog CAV1/ Caveolin-1 CLIA Kit
Caveolin-1

货号:

U0214d

商标:

EIAab^®

监管等级:

RUO

别名:

Vesicular integral-membrane protein VIP21, CAV

检测方法:

CLIA

特异性:

Natural and recombinant dog Caveolin-1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Dog CAV1 CLIA Kit

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产品说明书

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Homooligomer. Interacts with BMX, BTK, GLIPR2, NOSTRIN, SNAP25 and syntaxin (By similarity). Interacts (via the N-terminus) with DPP4; the interaction is direct (By similarity). Interacts with CTNNB1, CDH1 and JUP.

功能:

Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

亚细胞位置:

Golgi apparatus membrane Peripheral membrane protein Cell membrane Peripheral membrane protein Membrane caveola Peripheral membrane protein Membrane raft Colocalized with DPP4 in membrane rafts (By similarity). Potential hairpin-like structure in the membrane. Membrane protein of caveolae.

数据库链接

Uniprot:

P33724

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