CTSB (基因名), Cathepsin B (蛋白名), catb_human.
产品名称:
Human CTSB/ Cathepsin B CLIA Kit
组织蛋白酶B
货号:
U0405h
商标:
EIAab®
监管等级:
别名:
APP secretase, Cathepsin B1, APPS, CPSB
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Cathepsin B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Interacts with SRPX2. Directly interacts with SHKBP1 (PubMed:16733801).
功能:
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:12220505). Cleaves matrix extracellular phosphoglycoprotein MEPE (PubMed:12220505). Has also been implicated in tumor invasion and metastasis (PubMed:3972105).
亚细胞位置:
Lysosome
Melanosome
Secreted
Extracellular space
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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