CALR (基因名), Calreticulin (蛋白名), calr_canfa.
产品名称:
Dog CALR/ Calreticulin CLIA Kit
Calreticulin
货号:
U1486d
商标:
EIAab®
监管等级:
别名:
CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, ERp60
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant dog Calreticulin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Epigenetics
通用注释
亚单元:
Monomer. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with GABARAP, NR3C1, PDIA3/ERp57 and TRIM21.
功能:
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.
亚细胞位置:
Endoplasmic reticulum lumen
验证序列:
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