CACNA1S (基因名), Voltage-dependent L-type calcium channel subunit alpha-1S (蛋白名), cac1s_chick.
产品名称:
Chicken CACNA1S/ Voltage-dependent L-type calcium channel subunit alpha-1S CLIA Kit
货号:
U11658c
商标:
EIAab®
监管等级:
别名:
Voltage-gated calcium channel subunit alpha Cav1.1
检测方法:
CLIA
特异性:
Natural and recombinant chicken Voltage-dependent L-type calcium channel subunit alpha-1S
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2 (By similarity). CACNA1S channel activity is modulated by the auxiliary subunits (CACNB1 or CACNB2, CACNG1 and CACNA2D1). Interacts with DYSF and JSRP1 (By similarity). Interacts with RYR1 (By similarity). Interacts with CALM (By similarity).
功能:
Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.
亚细胞位置:
Cell membrane
Sarcolemma
T-tubule
Multi-pass membrane protein
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