Rat C5ar1/ C5a anaphylatoxin chemotactic receptor 1 CLIA Kit
C5a过敏性毒素趋化受体

货号:

U9156r

商标:

EIAab^®

监管等级:

RUO

别名:

C5a anaphylatoxin chemotactic receptor, C5a-R, CD88, C5r1

检测方法:

CLIA

特异性:

Natural and recombinant rat C5a anaphylatoxin chemotactic receptor 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Rat C5ar1 CLIA Kit

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通用注释

亚单元:

Homodimer. May also form higher-order oligomers (By similarity). Interacts (when phosphorylated) with ARRB1 and ARRB2; the interaction is associated with internalization of C5aR (PubMed:12464600).

功能:

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:9464523). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (By similarity). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:9464523).

亚细胞位置:

Cell membrane Multi-pass membrane protein Cytoplasmic vesicle Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles.

数据库链接

UniGene:

Rn.10680

STRING:

10116.ENSRNOP00000064558

KEGG:

rno:113959

Pfam:

PF00001

Uniprot: