Rat Bcl10/ B-cell lymphoma/leukemia 10 CLIA Kit
B细胞淋巴瘤/白血病10

货号:

U9627r

商标:

EIAab^®

监管等级:

RUO

别名:

B-cell CLL/lymphoma 10, R-RCD1, Bcl-10, RCD

检测方法:

CLIA

特异性:

Natural and recombinant rat B-cell lymphoma/leukemia 10

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Rat Bcl10 CLIA Kit

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通用注释

亚单元:

Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. Self-associates by CARD-CARD interaction and interacts with other CARD-proteins such as CARD9, CARD10, CARD11 and CARD14. Binds caspase-9 with its C-terminal domain (By similarity). Interacts with TRAF2 and BIRC2/c-IAP2. Interacts with PELI2 and SOCS3; these interactions may be mutually exclusive.

功能:

Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

亚细胞位置:

Cytoplasm Membrane raft Colocalized with DPP4 in membrane rafts.

数据库链接

UniGene:

Rn.13007

SMR:

Q9QYN5

STRING:

10116.ENSRNOP00000019911

KEGG:

rno:83477

Pfam: