Human BCAP31/ B-cell receptor-associated protein 31 CLIA Kit
b细胞受体相关蛋白

货号:

U14114h

商标:

EIAab^®

监管等级:

RUO

别名:

6C6-AG tumor-associated antigen, Protein CDM, p28, BCR-associated protein 31, BAP31, DXS1357E

检测方法:

CLIA

特异性:

Natural and recombinant human B-cell receptor-associated protein 31

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Human BCAP31 CLIA Kit

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通用注释

亚单元:

Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with HACD2 (PubMed:15024066).

功能:

Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis.

亚细胞位置:

Endoplasmic reticulum membrane Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane Multi-pass membrane protein May shuttle between the ER and the intermediate compartment/cis-Golgi complex.

数据库链接

UniGene:

Hs.522817

SMR:

P51572

STRING:

9606.ENSP00000392330

KEGG:

hsa:10134

MIM:

300398

Pfam: