BAG4 (基因名), BAG family molecular chaperone regulator 4 (蛋白名), bag4_human.
产品名称:
Human BAG4/ BAG family molecular chaperone regulator 4 CLIA Kit
货号:
U11651h
商标:
EIAab®
监管等级:
别名:
Bcl-2-associated athanogene 4, Silencer of death domains, BAG-4, SODD
检测方法:
CLIA
特异性:
Natural and recombinant human BAG family molecular chaperone regulator 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Binds to the ATPase domain of HSP/HSC70 chaperones. Binds to the death domain of TNFRSF1A in the absence of TNF and thereby prevents binding of adapter molecules such as TRADD or TRAF2. Binds to the death domain of TNFRSF12. Interacts with PARK2.
功能:
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.
亚细胞位置:
Cytoplasm
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