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ASAP2 (基因名), Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (蛋白名), asap2_human.

产品名称:

Human ASAP2/ Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 CLIA Kit

货号:

U13911h

商标:

EIAab^®

监管等级:

RUO

别名:

Development and differentiation-enhancing factor 2, Paxillin-associated protein with ARF GAP activity 3, Pyk2 C-terminus-associated protein, PAG3, PAP, DDEF2, KIAA0400

检测方法:

CLIA

特异性:

Natural and recombinant human Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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通用注释

亚单元:

Binds PXN, ARF1, ARF5, ARF6, PTK2B and SRC.

功能:

Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.

亚细胞位置:

Cytoplasm Golgi apparatus Golgi stack membrane Peripheral membrane protein Cell membrane Peripheral membrane protein Colocalizes with F-actin and ARF6 in phagocytic cups.

数据库链接

UniGene:

Hs.555902

SMR:

O43150

STRING:

9606.ENSP00000281419

KEGG:

hsa:8853

MIM:

603817

Pfam: