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Asap1 (基因名), Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (蛋白名), asap1_rat.

产品名称:

Rat Asap1/ Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

130 kDa phosphatidylinositol 4, 5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, Development and differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP, ARF GTPase-activating protein 1, DEF-1, Ddef1

检测方法:

CLIA

特异性:

Natural and recombinant rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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产品说明书

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通用注释

亚单元:

Homodimer. Interacts with SRC and CRK. Interacts with RAB11FIP3. Interacts with PTK2B/PYK2. Interacts with CTTN. Interacts (via SH3 domain) with APC.

功能:

Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis.

亚细胞位置:

Cytoplasm Membrane Predominantly cytoplasmic. Partially membrane-associated (By similarity).

数据库链接

UniGene:

Rn.63466

STRING:

10116.ENSRNOP00000059763

KEGG:

rno:314961

Pfam:

PF12796

Uniprot: