Arap3 (基因名), Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (蛋白名), arap3_mouse.
产品名称:
Mouse Arap3/ Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Centaurin-delta-3, Dual specificity Rho- and Arf-GTPase-activating protein 1, Cnt-d3, Centd3, Drag1, Kiaa4097
检测方法:
CLIA
特异性:
Natural and recombinant mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts (via SAM domain) with INPPL1/SHIP2.
功能:
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts preferentially on ARF5 and on RHOA.
亚细胞位置:
Cytoplasm
Cell membrane
Peripheral membrane protein
Cytoplasm
Cytoskeleton
Cell projection
Lamellipodium
Cell projection
Ruffle
Cytoplasmic, and associated with F-actin-rich membrane ruffles and lamellipodia.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
验证序列:
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