ANGPT1 (基因名), Angiopoietin-1 (蛋白名), angp1_canfa.
通用注释
亚单元:
N/A
功能:
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
亚细胞位置:
Secreted
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