Agap2 (基因名), Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (蛋白名), agap2_rat.
产品名称:
Rat Agap2/ Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Centaurin-gamma-1, Phosphatidylinositol 3-kinase enhancer, Cnt-g1, PIKE, AGAP-2, Centg1
检测方法:
CLIA
特异性:
Natural and recombinant rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2.
功能:
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. Aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase.
亚细胞位置:
Cytoplasm
Nucleus
数据库链接
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