AFAP1 (基因名), Actin filament-associated protein 1 (蛋白名), afap1_chick.
产品名称:
Chicken AFAP1/ Actin filament-associated protein 1 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
110 kDa actin filament-associated protein, Neural actin filament protein, pp110, AFAP-110
检测方法:
CLIA
特异性:
Natural and recombinant chicken Actin filament-associated protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Monomer and homomultimer. Interacts via its C-terminus with F-actin; probably involving AFAP1 multimers. Interacts with activated SRC SH3-SH2 domains. May interact with FYN SH3-SH2 domains. Interacts via its PH 1 domain with PRKCA, PRKCB, PRKCI.
功能:
Function as an adapter molecule that links other proteins to the actin cytoskeleton. May function in facilitating interactions between SRC and actin filaments. May modulate changes in actin filament integrity and induce lamellipodia formation. Can cross-link actin filaments into both network and bundle structures.
亚细胞位置:
Cytoplasm
Cytoskeleton
Localizes with stress fibers in quiescent cells, concentrated in cell motility structures such as lamellipodia, filopodia and membrane ruffles upon their induction.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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