Abca7 (基因名), ATP-binding cassette sub-family A member 7 (蛋白名), abca7_rat.
产品名称:
Rat Abca7/ ATP-binding cassette sub-family A member 7 CLIA Kit
ATP结合盒亚家族A7
货号:
U15004r
商标:
EIAab®
监管等级:
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant rat ATP-binding cassette sub-family A member 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
Golgi apparatus membrane
Multi-pass membrane protein
Endosome membrane
Multi-pass membrane protein
Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.
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