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首页  >  化学发光试剂盒  >  Rat A1m CLIA Kit
A1m (基因名), Alpha-1-macroglobulin (蛋白名), A1M_RAT.
产品名称:

Rat A1m/ Alpha-1-macroglobulin CLIA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Alpha-1-M, Alpha-1-macroglobulin 165 kDa subunit, Pzp

检测方法:
CLIA
特异性:
Natural and recombinant rat Alpha-1-macroglobulin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat A1m CLIA Kit
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产品说明书


通用注释


Sub Unit:
Homotetramer; disulfide-linked.


Function:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.


Subcellular Location:
Secreted


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