NUDT1 (基因名), 7,8-dihydro-8-oxoguanine triphosphatase (蛋白名), 8ODP_HUMAN.
产品名称:
Human NUDT1/ 7,8-dihydro-8-oxoguanine triphosphatase CLIA Kit
7,8-二氢-8氧桥鸟嘌呤三磷酸
货号:
U3104h
商标:
EIAab®
监管等级:
别名:
2-hydroxy-dATP diphosphatase, 8-oxo-dGTPase, Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1, MTH1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
109-7000pg/mL
特异性:
Natural and recombinant human 7,8-dihydro-8-oxoguanine triphosphatase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Monomer.
功能:
Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
亚细胞位置:
Isoform p26
Cytoplasm
Mitochondrion matrix
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