027-59234612(+86)
EIAab
首页  >  化学发光试剂盒  >  Human NUDT1 CLIA Kit
NUDT1 (基因名), 7,8-dihydro-8-oxoguanine triphosphatase (蛋白名), 8ODP_HUMAN.
产品名称:

Human NUDT1/ 7,8-dihydro-8-oxoguanine triphosphatase CLIA Kit
7,8-二氢-8氧桥鸟嘌呤三磷酸

货号:

U3104h

商标:
EIAab®
监管等级:
别名:

2-hydroxy-dATP diphosphatase, 8-oxo-dGTPase, Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1, MTH1

检测方法:
CLIA
实验类型:
Sandwich
检测范围:
109-7000pg/mL
特异性:
Natural and recombinant human 7,8-dihydro-8-oxoguanine triphosphatase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human NUDT1 CLIA Kit
规格 & 价格: 登录.
×
Human NUDT1 CLIA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
Monomer.


Function:
Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.


Subcellular Location:
Isoform p26 Cytoplasm Mitochondrion matrix


该产品尚未在任何出版物中被引用。

[1].
"Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk."

[2].
"Association study of human MTH1 gene polymorphisms with type 1 diabetes mellitus."

[3].
"Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis."

[4].
"Association study of human MTH1 Ile45Thr polymorphism with sporadic Parkinson's disease."

[5].
"Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas."

[6].
"MYH, OGG1, MTH1, and APC alterations involved in the colorectal tumorigenesis of Korean patients with multiple adenomas."

[7].
"Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer."

[8].
"Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis."

[9].
"The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal."

[10].
"Germline susceptibility to colorectal cancer due to base-excision repair gene defects."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 价格 ($) 小计 1 ($)
小计 2: $
triangle
规格 数量 价格 ($)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59759960(+86)
邮箱:sales@eiaab.com