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SCG5 (基因名), Neuroendocrine protein 7B2 (蛋白名), 7B2_HUMAN.
产品名称:

Human SCG5/ Neuroendocrine protein 7B2 CLIA Kit
神经内分泌蛋白7B2

货号:

U9861h

商标:
EIAab®
监管等级:
别名:

Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I, SGNE1

检测方法:
CLIA
特异性:
Natural and recombinant human Neuroendocrine protein 7B2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Human SCG5 CLIA Kit
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Human SCG5 CLIA Kit
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通用注释


亚单元:
Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.


功能:
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.


亚细胞位置:
Secreted Neuroendocrine and endocrine secretory granules.


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