Htr6 (基因名), 5-hydroxytryptamine receptor 6 (蛋白名), 5HT6R_RAT.
产品名称:
Rat Htr6/ 5-hydroxytryptamine receptor 6 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
5-HT-6, ST-B17, Serotonin receptor 6
检测方法:
CLIA
特异性:
Natural and recombinant rat 5-hydroxytryptamine receptor 6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
Sub Unit:
Interacts with MTOR, RPTOR and NF1 (By similarity). Interacts with CDK5.
Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (PubMed:7680751). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
验证序列:
该产品尚未在任何出版物中被引用。
[2].
"No association of 5-HT2C, 5-HT6, and tryptophan hydroxylase-1 gene polymorphisms with personality traits in the Japanese population."
[4].
"Risperidone response and 5-HT6 receptor gene variance: genetic association analysis with adjustment for nongenetic confounders."
[5].
"Association of the HTR6 polymorphism C267T with late-onset Alzheimer's disease in Chinese."
[6].
"5-Hydroxytryptamine 6 receptor (5-HT(6)) receptor and apolipoprotein E (ApoE) polymorphisms in patients with Alzheimer's disease in the Basque Country."
[8].
"Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia."
[9].
"Serotonin 6 receptor polymorphism in schizophrenia: frequency, age at onset and cognitive function."
[10].
"Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease."
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