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Htr6 (基因名), 5-hydroxytryptamine receptor 6 (蛋白名), 5HT6R_MOUSE.
产品名称:

Mouse Htr6/ 5-hydroxytryptamine receptor 6 CLIA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT-6, Serotonin receptor 6

检测方法:
CLIA
特异性:
Natural and recombinant mouse 5-hydroxytryptamine receptor 6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Htr6 CLIA Kit
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Mouse Htr6 CLIA Kit
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产品说明书


通用注释


Sub Unit:
Interacts with CDK5 (PubMed:25078650). Interacts with MTOR (PubMed:23027611). Interacts with RPTOR and NF1.


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (PubMed:25078650). Is an activator of TOR signaling (PubMed:23027611).


Subcellular Location:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Risperidone-related weight gain: genetic and nongenetic predictors."

[2].
"No association of 5-HT2C, 5-HT6, and tryptophan hydroxylase-1 gene polymorphisms with personality traits in the Japanese population."

[3].
"Serotonergic genes and personality traits in the Korean population."

[4].
"Risperidone response and 5-HT6 receptor gene variance: genetic association analysis with adjustment for nongenetic confounders."

[5].
"Association of the HTR6 polymorphism C267T with late-onset Alzheimer's disease in Chinese."

[6].
"5-Hydroxytryptamine 6 receptor (5-HT(6)) receptor and apolipoprotein E (ApoE) polymorphisms in patients with Alzheimer's disease in the Basque Country."

[7].
"[Associations between six functional genes and schizophrenia]."

[8].
"Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia."

[9].
"Serotonin 6 receptor polymorphism in schizophrenia: frequency, age at onset and cognitive function."

[10].
"Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease."
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