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Htr4 (基因名), 5-hydroxytryptamine receptor 4 (蛋白名), 5HT4R_RAT.
产品名称:

Rat Htr4/ 5-hydroxytryptamine receptor 4 CLIA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT-4, Serotonin receptor 4

检测方法:
CLIA
特异性:
Natural and recombinant rat 5-hydroxytryptamine receptor 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Htr4 CLIA Kit
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产品说明书


通用注释


Sub Unit:
May interact with PATJ, MAGI2, MPP3, NOS1, SLC9A3R1, SEC23A and SNX27. May form a complex including SLC9A3R1 and EZR (By similarity). Interacts (via C-terminus 330-346 AA) with GRK5; this interaction is promoted by 5-HT (serotonin).


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.


Subcellular Location:
Cell membrane Multi-pass membrane protein Endosome Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.


该产品尚未在任何出版物中被引用。

[1].
"Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia."

[2].
"Cloning, expression, and pharmacology of four human 5-hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus."

[3].
"Expression of serotonin receptor mRNAs in blood vessels."

[4].
"Association study of the serotoninergic system in migraine in the Spanish population."

[5].
"Lack of association between HTR4 gene polymorphisms and schizophrenia in case-control and family-based samples."
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