Pig HTR4/ 5-hydroxytryptamine receptor 4 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Serotonin receptor 4, 5-HT-4

检测方法:

CLIA

特异性:

Natural and recombinant pig 5-hydroxytryptamine receptor 4

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Pig HTR4 CLIA Kit

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产品说明书

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通用注释

亚单元:

May interact with PATJ, MAGI2, MPP3, NOS1, SLC9A3R1, SEC23A and SNX27. May form a complex including SLC9A3R1 and EZR.

功能:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

亚细胞位置:

Cell membrane Multi-pass membrane protein Endosome Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Interacts (via C-terminus) with GRK5; this interaction is promoted by 5-HT (serotonin).

数据库链接

UniGene:

Ssc.16140

Pfam:

PF00001

Uniprot:

Q29006

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