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HTR4 (基因名), 5-hydroxytryptamine receptor 4 (蛋白名), 5HT4R_PIG.
产品名称:

Pig HTR4/ 5-hydroxytryptamine receptor 4 CLIA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

5-HT-4, Serotonin receptor 4

检测方法:
CLIA
特异性:
Natural and recombinant pig 5-hydroxytryptamine receptor 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig HTR4 CLIA Kit
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产品说明书


通用注释


Sub Unit:
May interact with PATJ, MAGI2, MPP3, NOS1, SLC9A3R1, SEC23A and SNX27. May form a complex including SLC9A3R1 and EZR.


Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.


Subcellular Location:
Cell membrane Multi-pass membrane protein Endosome Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Interacts (via C-terminus) with GRK5; this interaction is promoted by 5-HT (serotonin).


该产品尚未在任何出版物中被引用。

[1].
"Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia."

[2].
"Cloning, expression, and pharmacology of four human 5-hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus."

[3].
"Expression of serotonin receptor mRNAs in blood vessels."

[4].
"Association study of the serotoninergic system in migraine in the Spanish population."

[5].
"Lack of association between HTR4 gene polymorphisms and schizophrenia in case-control and family-based samples."
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