Mouse Htr4/ 5-hydroxytryptamine receptor 4 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Serotonin receptor 4, 5-HT-4

检测方法:

CLIA

特异性:

Natural and recombinant mouse 5-hydroxytryptamine receptor 4

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Mouse Htr4 CLIA Kit

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通用注释

亚单元:

Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with PATJ, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR. Interacts (via C-terminus 330-346 AA) with GRK5; this interaction is promoted by 5-HT (serotonin).

功能:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

亚细胞位置:

Cell membrane Multi-pass membrane protein Endosome Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.

数据库链接

UniGene:

Mm.20440

STRING:

10090.ENSMUSP00000027560

KEGG:

mmu:15562

Pfam:

PF00001

Uniprot:

P97288

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