HTR1B (基因名), 5-hydroxytryptamine receptor 1B (蛋白名), 5HT1B_HUMAN.
产品名称:
Human HTR1B/ 5-hydroxytryptamine receptor 1B CLIA Kit
5 -羟色胺受体1 b
货号:
U10279h
商标:
EIAab®
监管等级:
别名:
S12, Serotonin 1D beta receptor, Serotonin receptor 1B, 5-HT-1D-beta, 5-HT-1B, HTR1DB
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
10.9-700pg/mL
特异性:
Natural and recombinant human 5-hydroxytryptamine receptor 1B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Homodimer. Heterodimer with HTR1D.
功能:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
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