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Eif4ebp3 (基因名), Eukaryotic translation initiation factor 4E-binding protein 3 (蛋白名), 4EBP3_MOUSE.
产品名称:

Mouse Eif4ebp3/ Eukaryotic translation initiation factor 4E-binding protein 3 CLIA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

4E-BP3

检测方法:
CLIA
特异性:
Natural and recombinant mouse Eukaryotic translation initiation factor 4E-binding protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Eif4ebp3 CLIA Kit
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产品说明书


通用注释


Sub Unit:
EIF4EBP3 interacts with EIF4E.


Function:
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.


Subcellular Location:
N/A


该产品尚未在任何出版物中被引用。

[1].
"4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family."

[2].
"Binding preference of eIF4E for 4E-binding protein isoform and function of eIF4E N-terminal flexible region for interaction, studied by SPR analysis."

[3].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[4].
"Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK."

[5].
"Localisation and regulation of the eIF4E-binding protein 4E-BP3."

[6].
"MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells."

[7].
"Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3."

[8].
"Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism."

[9].
"A proteome-scale map of the human interactome network."

[10].
"LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells."
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