EPB41 (基因名), Protein 4.1 (蛋白名), 41_HUMAN.
通用注释
亚单元:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin, CENPJ and DLG1. Also found to associate with contractile apparatus and tight junctions.
功能:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.
亚细胞位置:
Cytoplasm
Cytoskeleton
Cytoplasm
Cell cortex
Nucleus
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