EPB41 (基因名), Erythroid protein 4.1 (蛋白名), 41_CHICK.
通用注释
亚单元:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin and DLG1.
功能:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. May be required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
亚细胞位置:
Nucleus
Cytoplasm
Cytoskeleton
Cytoplasm
Cell cortex
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