Sh3bp5 (基因名), SH3 domain-binding protein 5 (蛋白名), 3BP5_MOUSE.
产品名称:
Mouse Sh3bp5/ SH3 domain-binding protein 5 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
SH3 domain-binding protein that preferentially associates with BTK, SH3BP-5, Sab
检测方法:
CLIA
特异性:
Natural and recombinant mouse SH3 domain-binding protein 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with BTK (By similarity). Interacts with all isoforms of MAPK8, MAPK9, MAPK10 and MAPK12 (By similarity). Interacts with GDP-bound and nucleotide-free forms of RAB11A (PubMed:26506309).
功能:
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
亚细胞位置:
Mitochondrion
数据库链接
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