Hsd3b7 (基因名), 3 beta-hydroxysteroid dehydrogenase type 7 (蛋白名), 3BHS7_MOUSE.
产品名称:
Mouse Hsd3b7/ 3 beta-hydroxysteroid dehydrogenase type 7 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, Cholest-5-ene-3-beta, 7-alpha-diol 3-beta-dehydrogenase, 3-beta-HSD VII, C(27) 3-beta-HSD
检测方法:
CLIA
特异性:
Natural and recombinant mouse 3 beta-hydroxysteroid dehydrogenase type 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (PubMed:22999953).
亚细胞位置:
Endoplasmic reticulum membrane
Multi-pass membrane protein
数据库链接
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