YWHAQ (基因名), 14-3-3 protein theta (蛋白名), 1433t_human.
产品名称:
Human YWHAQ/ 14-3-3 protein theta CLIA Kit
1433蛋白θ
货号:
U14293h
商标:
EIAab®
监管等级:
别名:
14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
109-7000pg/mL
特异性:
Natural and recombinant human 14-3-3 protein theta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cancer
精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。
Sample Type |
Average(%) |
Recovery Range(%) |
Serum |
99 |
91-103 |
Plasma |
98 |
93-106 |
线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。
Sample |
1:2 |
1:4 |
1:8 |
1:16 |
serum(n=5) |
92-105% |
90-101% |
95-105% |
92-109% |
EDTA plasma(n=5) |
89-95% |
93105% |
89-94% |
90-106% |
heparin plasma(n=5) |
93-104%
|
94-110% |
101-111% |
91-110% |
通用注释
亚单元:
Homodimer. Interacts with CDK16 (By similarity). Interacts with RGS7 (phosphorylated form) (PubMed:10862767). Interacts with SSH1. Interacts with CDKN1B ('Thr-198' phosphorylated form); the interaction translocates CDKN1B to the cytoplasm. Interacts with GAB2. Interacts with the 'Ser-241' phosphorylated form of PDPK1. Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with SLITRK1 (PubMed:19640509).
功能:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
亚细胞位置:
Cytoplasm
In neurons, axonally transported to the nerve terminals.
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