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YWHAQ (基因名), 14-3-3 protein theta (蛋白名), 1433T_HUMAN.

产品名称:

Human YWHAQ/ 14-3-3 protein theta CLIA Kit
1433蛋白θ

货号:

U14293h

商标:

EIAab^®

监管等级:

RUO

别名:

14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

109-7000pg/mL

特异性:

Natural and recombinant human 14-3-3 protein theta

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

精密度

批内差：已知浓度的3个样本在一个板子内重复检测20次，以评估批内精密度。
批内 CV： 3.9%
批间差：已知浓度的3个样本在不同的板子上重复测定5次，以评估测定批间精密度。
批间 CV： 7.7%

回收率

回收率：低、中和高浓度的分析物被掺入到血清或者血浆样本中，进行回收实验测定。

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

线性

线性：给定样本通过梯度稀释，每次稀释的测量值与理论值的比值。

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

通用注释

亚单元:

Homodimer. Interacts with CDK16 (By similarity). Interacts with RGS7 (phosphorylated form) (PubMed:10862767). Interacts with SSH1. Interacts with CDKN1B ('Thr-198' phosphorylated form); the interaction translocates CDKN1B to the cytoplasm. Interacts with GAB2. Interacts with the 'Ser-241' phosphorylated form of PDPK1. Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with SLITRK1 (PubMed:19640509).

功能:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

亚细胞位置:

Cytoplasm In neurons, axonally transported to the nerve terminals.

数据库链接

UniGene:

Hs.74405

SMR:

P27348

STRING:

9606.ENSP00000238081

KEGG:

hsa:10971

MIM: