027-59234612(+86)
EIAab
首页  >  化学发光试剂盒  >  Human YWHAQ CLIA Kit
YWHAQ (基因名), 14-3-3 protein theta (蛋白名), 1433T_HUMAN.
产品名称:

Human YWHAQ/ 14-3-3 protein theta CLIA Kit
1433蛋白θ

货号:

U14293h

商标:
EIAab®
监管等级:
别名:

14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1

检测方法:
CLIA
实验类型:
Sandwich
检测范围:
109-7000pg/mL
特异性:
Natural and recombinant human 14-3-3 protein theta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Human YWHAQ CLIA Kit
规格 & 价格: 登录.
×
Human YWHAQ CLIA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS


精密度

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: 3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: 7.7%

回收率
Recovery was determined by spiking various levels of 14-3-3 protein theta into serum and plasma.

Sample Type

Average(%)

Recovery Range(%)

Serum

99

91-103

Plasma

98

93-106

 

 

 

 

线性
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of 14-3-3 protein theta and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

92-105%

90-101%

95-105%

92-109%

EDTA plasma(n=5)

89-95%

93105%

89-94%

90-106%

heparin plasma(n=5)

93-104%

 

94-110%

101-111%

91-110%

 

通用注释


Sub Unit:
Homodimer. Interacts with CDK16 (By similarity). Interacts with RGS7 (phosphorylated form) (PubMed:10862767). Interacts with SSH1. Interacts with CDKN1B ('Thr-198' phosphorylated form); the interaction translocates CDKN1B to the cytoplasm. Interacts with GAB2. Interacts with the 'Ser-241' phosphorylated form of PDPK1. Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with SLITRK1 (PubMed:19640509).


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.


Subcellular Location:
Cytoplasm In neurons, axonally transported to the nerve terminals.


该产品尚未在任何出版物中被引用。

[1].
"A 14-3-3 mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord."

[2].
"An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes."

[3].
"Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils."

[4].
"ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding."

[5].
"Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study."

[6].
"SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner."

[7].
"Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein."

[8].
"Structural basis for protein-protein interactions in the 14-3-3 protein family."

[9].
"A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 价格 ($) 小计 1 ($)
小计 2: $
triangle
规格 数量 价格 ($)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59759960(+86)
邮箱:sales@eiaab.com