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Ywhah (基因名), 14-3-3 protein eta (蛋白名), 1433F_RAT.
产品名称:

Rat Ywhah/ 14-3-3 protein eta CLIA Kit

货号:

U14292r

商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant rat 14-3-3 protein eta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Rat Ywhah CLIA Kit
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产品说明书


通用注释


Sub Unit:
Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Weakly interacts with CDKN1B. Interacts with ARHGEF28 and CDK16. Interacts with GAB2 (By similarity). Interacts with KCNK18 in a phosphorylation-dependent manner. Interacts with SAMSN1 (By similarity). Interacts with the 'Ser-241' phosphorylated form of PDPK1 (By similarity). Interacts with the 'Thr-369' phosphorylated form of DAPK2 (By similarity). Interacts with PI4KB, TBC1D22A and TBC1D22B (By similarity). Interacts with SLITRK1.


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.


Subcellular Location:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Systematic screening of the 14-3-3 eta (eta) chain gene for polymorphic variants and case-control analysis in schizophrenia."

[2].
"14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia."

[3].
"The human and bovine 14-3-3 eta protein mRNAs are highly conserved in both their translated and untranslated regions."

[4].
"cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain."

[5].
"ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding."

[6].
"Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study."

[7].
"Family-based association of YWHAH in psychotic bipolar disorder."

[8].
"SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner."

[9].
"Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein."

[10].
"Structural basis for protein-protein interactions in the 14-3-3 protein family."
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