YWHAB (基因名), 14-3-3 protein beta/alpha (蛋白名), 1433B_HUMAN.
产品名称:
Human YWHAB/ 14-3-3 protein beta/alpha CLIA Kit
货号:
U14289h
商标:
EIAab®
监管等级:
别名:
Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1
检测方法:
CLIA
特异性:
Natural and recombinant human 14-3-3 protein beta/alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
(Microbial infection) Interacts with herpes simplex virus 1 protein UL46.
功能:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
亚细胞位置:
Cytoplasm
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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