General 5METHF/ Levomefolic acid CLIA Kit
Levomefolic酸

货号:

U15141Ge

商标:

EIAab^®

监管等级:

RUO

别名:

5-Methyltetrahydrofolate

检测方法:

CLIA

特异性:

Natural and recombinant general Levomefolic acid

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

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General 5METHF CLIA Kit

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Levomefolic acid (also known as 5-MTHF, L-methylfolate and 5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. In the cell, L-methylfolate is used in the methylation of homocysteine to form methionine and tetrahydrofolate (THF). THF is the immediate acceptor of one carbon units for the synthesis of thymidine-DNA, purines (RNA and DNA) and methionine. The un-methylated form, folic acid (vitamin B9), is a synthetic form of folate, and must undergo enzymatic reduction by methylenetetrahydrofolate reductase (MTHFR) to become biologically active.

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