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首页  >  化学发光试剂盒  >  General GSH CLIA Kit
GSH (短名 ),
产品名称:

General GSH/ Glutathione CLIA Kit
谷胱甘肽

货号:

U9182Ge

商标:
EIAab®
监管等级:
检测方法:
CLIA
实验类型:
Competitive
检测范围:
0.156-10ng/mL
特异性:
Natural and recombinant general Glutathione
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
General GSH CLIA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
N/A


Function:
Glutathione (GSH) is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. Thiol groups are reducing agents, existing at a concentration of approximately 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmic proteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form, glutathione disulfide (GSSG), also called L-(–)-glutathione. Once oxidized, glutathione can be reduced back by glutathione reductase, using NADPH as an electron donor. The ratio of reduced glutathione to oxidized glutathione within cells is often used as a measure of cellular toxicity.


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