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SAM (短名 ),
产品名称:

General SAM/ S-Adenosyl methionine CLIA Kit

货号:

U14920Ge

商标:
EIAab®
监管等级:
检测方法:
CLIA
实验类型:
Competitive
检测范围:
0.195-12.5nmol/L
特异性:
Natural and recombinant general S-Adenosyl methionine
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
General SAM CLIA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


Sub Unit:
N/A


Function:
S-Adenosyl methionine (ademetionine, AdoMet, SAM, SAMe, SAM-e) is a common cosubstrate involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates, such as nucleic acids, proteins, lipids and secondary metabolites. In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.


Location:
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