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首页  >  化学发光试剂盒  >  Rat C-Peptide CLIA Kit
C-Peptide (短名 ),
产品名称:

Rat C-Peptide CLIA Kit
C肽

货号:

U0447r

商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant rat C-Peptide
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Metabolism
Rat C-Peptide CLIA Kit
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产品说明书


通用注释


Sub Unit:
N/A


Function:
C-peptide is a protein that is produced in the body along with insulin. First preproinsulin is secreted with an A-chain, C-peptide, a B-chain, and a signal sequence. The signal sequence is cut off, leaving proinsulin. Then the C-peptide is cut off, leaving the A-chain and B-chain to form insulin.


Location:
Cellular effects of C-peptide: C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. The signal activates Ca2+-dependent intracellular signaling pathways such as MAPK, PLCγ, and PKC, leading to upregulation of a range of transcription factors as well as eNOS and Na+K+ATPase activities.



[1].
Do-Young Park, Young-Tae Ahn, Chul-Sung Huh, Robin A McGregor, and Myung-Sook Choi
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