Human PCT/ Procalcitonin CLIA Kit
降钙素原

货号:

U0689h

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

1.95-125pg/mL

特异性:

Natural and recombinant human Procalcitonin

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Signal Transduction

规格 & 价格:

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Human PCT CLIA Kit

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通用注释

亚单元:

N/A

功能:

The level of procalcitonin in the blood stream of healthy individuals is below the limit of detection (10 pg/mL) of clinical assays. The level of procalcitonin raises in a response to a proinflammatory stimulus, especially of bacterial origin. In this case, it is produced mainly by the cells of the lung and the intestine. It does not raise significantly with viral or non-infectious inflammations. With the derangements that a severe infection with an associated systemic response brings, the blood levels of procalcitonin may rise to 100 ng/ml. In serum, procalcitonin has a half-life of 25 to 30 hours. Remarkably the high procalcitonin levels produced during infections are not followed by a parallel increase in calcitonin or serum calcium levels.

Location:

Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine.

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